The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts
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چکیده
منابع مشابه
The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
Cell migration requires extension of lamellipodia that are stabilized by formation of adhesive complexes at the leading edge. Both processes are regulated by signaling proteins recruited to nascent adhesive sites that lead to activation of Rho GTPases. The Ajuba/Zyxin family of LIM proteins are components of cellular adhesive complexes. We show that cells from Ajuba null mice are inhibited in t...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-09024-4